Undoubtly, the answer is Yes!
More and more report shows Folic acid will mask Vitamin B12 deficiency
It's absorbed via liver and will increase liver burden.
It can’t be absorbed for variation in MTHFR C667T genotype
(NOTE: MTHFR is Polymorphism， CT &TT is the variation)
The most important, folic acid may increase the risk of congenital heart disease for baby.
Note: We are doing the pre-clinical and will publish the article in the beginning of 2018.
L-5-MTHF folate supplementation adding in dietary supplement would be a great contribution for human being’s health. Meanwhile, it’s a huge business prospects.
According to the statistic, the annual consumption of folic acid is 2000tons, half used in feed additive, 10-12% used in the field of medicine, almost 40% used in dietary and food supplements.