Nutritional Knowledge Of Folic Acid
- Aug 23, 2017 -

  Nutritional knowledge of folic acid

  In the last 20 years, since the US FDA and CDC found that folic acid supplementation in food can significantly reduce birth defects and reduce cardiovascular and cerebrovascular, peripheral vascular disease since the usual "folic acid" all of a sudden become "hot"!

  Folic acid, rich in green leaves because of the name, the first from the "spinach leaves" in the extraction of a water-soluble vitamins. In the "prevention of stroke," the work of the promotion, the general public really need to be good about the "folic acid" problem.

  First, the source

  1. Yeast, liver, fruit and green leafy vegetables are rich sources of folic acid. It is important to emphasize that folic acid in milk and egg yolk can be more easily absorbed by the human small intestine because it contains "butter monoglyceride".

  2. The synthesis of human intestinal flora.

  Second, the form of human existence

  In the human small intestine, after the biological reduction reaction, the resulting bioactive folic acid is a substance called "tetrahydrofolate". In the blood circulation, tetrahydrofolic acid in the form of "single glutamate" in the body; in the human body, tetrahydrofolic acid in the form of "polyglutamic acid".

  In general, the body of folic acid storage capacity of 3 to 4 months required.

  Third, the lack of folic acid hazards

  In general, folic acid in food is rich in content, as long as the normal diet with a reasonable, balanced nutrition, the body will not lack of folic acid. Only in the long-term lack of folic acid intake, intestinal absorption blocked, the body is too large consumption of folic acid in the case of the following hazards:

  1. erythrocyte anemia

  This is because folic acid deficiency, bone marrow erythrocyte DNA synthesis decreased, cell division rate decreased, the cell volume caused by larger. Can show weakness, dizziness, activity after palpitations and shortness of breath and other symptoms, blood tests show large cell positive pigment anemia.

  2. fetal neural tube defects

  Fetal neural tube defects mainly manifested as no brain, brain bulge, cerebrospinal meningeal, spina bifida / latent spina bifida, cleft lip and cleft palate and so on.


  Folic acid deficiency can cause hyperhomocysteinemia, thereby increasing the risk of arteriosclerosis, thrombosis, hypertension, cardiovascular and cerebrovascular diseases (such as stroke, myocardial infarction). Daily intake of 500 micrograms of folic acid is beneficial to the prevention of cardiovascular and cerebrovascular diseases.

  4. Increase the risk of cancer

  Because of the lack of folic acid can cause low methylation of DNA, which will increase the number of cancer, especially colon cancer, rectal cancer risk. Rich in folic acid foods can reduce the risk of these cancers.