What is the relationship between folic acid and pregnancy?
Folic acid is very important for women of childbearing age and pregnant women. Early lack of folic acid in pregnancy is the main cause of fetal neural tube defects. Nerve tube closure is 3 to 4 weeks in the embryonic development, folic acid deficiency can cause the nerve tube failed to close the spina bifida and no brain deformity-based neural tube deformity, mainly spina bifida and no brain and other central nervous abnormalities. No brain deformity for severe brain dysplasia, and skull defects, the general suffering from the disease of the baby before birth or birth within a short time after death. Spina bifida children can survive, but will become a permanent disability, the country and the family caused great losses. China is the world's brain and spinal cord defect in high incidence of the country. Each year, about 100,000 pregnant women produce brain and spinal cord defects, that is, three out of every 1,000 births suffer from this deficiency. The main reason is that Chinese women are generally lacking in folic acid during pregnancy and pregnancy. A folic acid application effect evaluation study confirmed that women from 1 month to 3 months before the daily increase of 680 micrograms of folic acid equivalent, can effectively reduce the high risk of birth defects in China, the incidence of neural tube defects in 85%.
Folic acid deficiency can not only increase the incidence of pregnancy-induced hypertension, placental abruption, but also lead to pregnant women suffering from megaloblastic anemia, fetal intrauterine growth retardation, premature birth and neonatal birth weight and so on.
To reduce the incidence of fetal brain and spinal cord defects, the most important thing is that women have begun to take enough folic acid during fertilization, but in fact many women know that after pregnancy began to add folic acid, and that time is usually fertilized One or two months, which will make the early fetal brain and spinal cord due to lack of adequate folic acid and development is not perfect, leading to the occurrence of brain and spinal cord defects. Therefore, experts recommend that women begin to add folic acid during the planned pregnancy period. Folic acid is not only important for early pregnancy, it is also essential throughout pregnancy. Pregnancy With the rapid growth of fetal body tissue, pregnant women need a lot of folic acid (usually 1.5 times the amount required) to meet the needs of the fetus. Experts believe that pregnant mothers need to add 600 to 800 micrograms of folic acid per day to meet the baby's growing needs and their own needs.