Statistically, depression affects more than 300 million people worldwide now, nearly half of whom live in Southeast Asia and the Western Pacific, including India and China.

According to the WTO, nearly 1 billion people worldwide shall have mental health problems after the COVID-19.
Methylfolate deficiency can lead to depression. Unlike folic acid, Magnafolate® can cross the blood-brain barrier directly.
Magnafolate® can repair the Hcy circulation and produce enough SAM (S-adenosine methionine) to normalize the methylation of bioamines and phospholipids in the central nervous system, thus promoting the synthesis of 5-ht.
Through regulation, tetrahydrobiopterin (BH4) is produced to affect the synthesis of neurotransmitters. Tetrahydrobiopterin (BH4) is an essential nutrient cofactor for the formation of monoamine neurotransmitters such as serotonin, dopamine and norepinephrine, all linked to mood regulation.

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