Is unmetabolized folic acid harmful—Magnafolate®?

Several studies indicate that chronically elevated levels of unmetabolized folic acid may have adverse health effects, including:

Increased cancer risk. High levels of unmetabolized folic acid have been associated with increased cancer risk. However, no evidence proves that unmetabolized folic acid plays a direct role.
risk of folic acid
Undetected B12 deficiency. Among elderly people, high folic acid levels can mask vitamin B12 deficiency. Untreated vitamin B12 deficiency may increase your risk of dementia and impair nerve function.

Even a small, daily dose of 400 mcg may cause unmetabolized folic acid to build up in your bloodstream.

Although high folic acid intake is a concern, the health implications are unclear, and further studies are needed.


Magnafolate® ,the Manufacturers & Supplier of active folate -Jinkang（The No.1 manufacture of L-Methylfolate Calcium in China, and No.2 worldwide, with much more experiences in exporting this material to North America, European, Brazil and etc..）


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