What Does L-5-Methylfolate Do | Magnafolate®

L-5-Methylfolate is the most important active form of folate.  Many people aren’t able to produce this form of folic acid, due to liver dysfunction or intestinal issues.

Another major reason is that the majority of Americans (3 out of 5) who have genetic variations in the enzyme known as L-5-Methylfolate-reductase cannot fully convert folic acid into the more useful 5-Methyltetrahydrofolate.

But it’s not all about preventing pregnancy-related issues either.  L-5-Methylfolate is also a key player in the production of many of our neurotransmitters like serotonin, dopamine, melatonin, epinephrine and norepinephrine. When neurotransmitter levels are supported, this helps to ensure a healthy overall mood. If a person is a poor converter of folic acid into L-5-Methylfolate, this can lead to mood issues and a variety of other health issues. 
What Does L-5-Methylfolate Do
Another area of importance for L-5-Methylfolate is how it works synergistically with vitamin B12 (or methylcobalamin, the active form) to help convert dangerous metabolic byproducts like homocysteine into methionine. Elevated levels of homocysteine are associated with heart disease and can be a sign of deficiencies of vitamins B6, B12 and folate. 

L-5-Methylfolate is important in any instance where folic acid (folate) is needed.  Everyone should ensure they receive enough folate in their diets and supplement if they're unsure. 


Magnafolate® ,the Manufacturers & Supplier of L-5-Methylfolate. 

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