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Does the MTHFR help people with depression? The MTHFR test shows whether or not a person has genetic variation in MTHFR. Knowing this information could be used by a healthcare provider if they are interested in using folate(L Methylfolate) as a treatment strategy for depression. The MTHFR test shows whether or not a person has genetic variation in MTHFR by evaluating the C677T polymorphism.
What are folic acid,folate,methylfolate and MTHFR? “Folate is a form of B vitamin that occurs naturally in many foods,” according to an article on the University of Michigan’s (U-M) health library website. “Folic acid is the man-made form of folate that is added to processed foods or vitamin and mineral supplements. Folate is needed in the human body for production of red blood cells.”
What is MTHFR and why is it important? MTHFR is an enzyme required to convert folic acid into an active form called L-methylfolate that is usable by our bodies. L-methylfolate plays an important role in making neurotransmitters such as serotonin, dopamine, and norepinephrine, which help regulate mood.
What are the key similarities of folic acid and L-methylfolate? L-methylfolate and folic acid are two types of biochemical compounds important in the metabolism of the body. They are important in DNA replication, utilizing amino acids, and in the formation of red blood cells.
What does a folic acid do for your body? Folic acid or vitamin B9 is the un-methylated and synthetic form of folate. Therefore, it has to undergo enzymatic reduction by dihydrofolate reductase (DHFR) to become folate, which is biologically active. Folate naturally occurs in the dark green vegetables, legumes, avocadoes, legumes, and in the liver in the biologically active form.
What is L Methylfolate? L-methylfolate or levomefolic acid is the biologically active form of folate. It circulates through the blood, and it even can cross the blood-brain barrier. For instance, it is important in DNA replication, cysteine cycle, and the regulation of homocysteine. Here, the cell uses l-methylfolate in the methylation of homocysteine to form methionine and tetrahydrofolate (THF).
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