What is 5-methyltetrahydrofolate?

Folate is a water-soluble vitamin that cannot be synthesized by human body itself and must be obtained by exogenous supplement. There is a lot of evidence that folate deficiency will lead to neural tube defects, some congenital malformations, dementia and some types of cancer. 

At present, the main form of folate supplementation is synthetic folic acid (FA), but its excessive supplementation will increase the potential risk of some diseases for oneself and offspring.
What is 5-methyltetrahydrofolate
5-methyltetrahydrofolate, also known as L-5-methyltetrahydrofolate, is the main natural form, which is more conducive to human absorption and utilization. Compared with synthetic folic acid FA, 5-methyltetrahydrofolate has no upper tolerance limit, which can be directly absorbed and utilized by the body to reduce the burden on the body.
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