Several factors affecting folate status

The World Health Organization (who) has also reported that many factors affect folate status, including genetics, such as MTHFR gene polymorphism. Other factors include physiological status (such as age, pregnancy, lactation); Biological factors (e.g., coexisting vitamin B6 and B12 status, homocysteine levels); Background factors (e.g., comorbidity); Moreover, the source of dietary folate is limited.

Since the association between MTHFR polymorphisms and low folate concentrations has been evaluated, direct prenatal vitamin supplementation of the active form of 5-MTHF may be very beneficial.
factors affecting folate status

Magnafolate® active folate (L-Methylfolate )—maximizes the folate supplementation delivering a "finished" folate the body can immediately use without any kind of metabolization.

Magnafolate® ,the Manufacturer & Supplier of active folate(L-Methylfolate).
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