Folate deficiency causes an anemia called megaloblastic anemia, in which the bone marrow produces abnormally large immature red blood cells. Symptoms include extreme fatigue, palpitations, shortness of breath, open ulcers on the tongue, and changes in skin or hair color.

Deficiency of folate and other B vitamins can lead to a disease called hyperhomocysteinemia, in which there is too much amino acid homocysteine in the blood. This may occur in people with kidney disease or genetic diseases that affect the production of 5-MTHF.
Chronic hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, Alzheimer's disease, recurrent miscarriage, and fracture in the elderly.
So we recommend:
Magnafolate® L-Methylfolate—maximizes the supplementation delivering a "finished" folate the body can immediately use without any kind of metabolization.
Jinkang Pharma ,the Manufacturer & Supplier of L-Methylfolate.