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Summary of folate and L-Methylfolate Folate, a B vitamin, is essential for building the body's genetic material. Many foods naturally contain folate, especially green leafy vegetables. Many manufacturers also use folic acid, a synthetic form of folate, to fortify cereals and grains. In addition, folic acid is provided as a supplement.
Supplemental source of folic acid and L-Methylfolate Although researchers once thought folic acid was more easily absorbed than folate, they now know that its metabolism is very slow. In addition, most of the folic acid you consume will remain metabolized and linger in the system. There are also concerns that the excessive accumulation of unmetabolized folic acid may promote tumor growth, although this has not been clearly confirmed.
5-MTHF and L-Methylfolate 5-MTHF is another form of folic acid supplement. In the United States, about 25% of Hispanics, 10%-15% of whites and 6% of African Americans have a genetic variation called MTHFR C677T. This variation further affects the ability to metabolize folic acid.
Something about folic acid Folic acid is the synthetic form of folate and is the most common form of supplementation. Manufacturers also use it for food fortification.
What are the side effects of folic acid? If you are pregnant, nursing, or lack folic acid, your provider may advise you to take folic acid. As an essential nutrient from food, folic acid is not associated with side effects or risks. However, taking supplements such as folic acid may have potential side effects. These side effects may be common or severe.
How do I know if I have folate deficiency Folic acid deficiency may need to be correctly identified and diagnosed by a healthcare provider through a specific laboratory. However, some identifying factors may indicate a defect. Megaloblastic anemia is a kind of anemia with a large number of red blood cells. It is a clinical symptom of folic acid deficiency. Symptoms include:
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