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What is methylfolate used for
What is methylfolate used for Methylfolate, which you can also take through supplementation, is the more active and natural form of folate. When we take folic acid, we rely on Methylenetetrahydrofolate reductase (MTHFR). This is both a gene and an enzyme that is found throughout our body. It converts folic acid to its active form, L-methylfolate. This process is critical to the body having enough folate.
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Active Folate for Heart Health
Active Folate for Heart Health According to extensive research, homocysteine plays an important role in preventing the risk factors leading to heart disease. An excessive accumulation of this amino acid in the blood - caused by an unhealthy lifestyle, a poor diet or even genetic factors - can in fact lead to cardiovascular disease (CVD), which still represents one of the major causes of mortality in the western world.
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Active folate for Cognitive Improvement
Active folate for Cognitive Improvement Cognitive impairment is a considerable health concern due to the exponentially increase of old population and is dictated by a large range of variables, some due to environmental factors, such as diet, and others due to genetics, such as the polymorphisms of methylentetrahydrofolate reductase (MTHFR) that impairs the folate conversion in the body.
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The active folate for mood
The active folate for mood Studies suggest the predominant role of folate deficiency in reducing neurotransmitter production and increasing homocysteine levels. The latter are the main factors in the development of mood disorders and depression. Moreover, the synthesis of tetrahydrobiopterin (BH4), cofactor of the synthesis of serotonin and dopamine, is suggested to be directly connected to folate level.
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The active folate for fertility
The active folate for fertility Infertility occurs for 48 million couples to 186 million individuals globally. Women and men with fertility problems may have low folate availability, which is often related to the MTHFR enzyme polymorphism.
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The benefit of acitve folate for pregnancy
The benefit of acitve folate for pregnancy Adequate folate level is primordial for pregnant women. Folate is a cofactor in cell growth, cell division, cell synthesis, and repair of DNA. During pregnancy, folate requirements increase to support embryonic and fetal development, maternal tissue growth, to reduce the risk of low birth weight, preterm birth, elevated homocysteine levels, and related adverse pregnancy outcomes.
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