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You need supplementary l-5-methylfolate The folate we obtain from the diet must be converted to its active form – called L-5-methylfolate – before it can help power the methylation cycle. However, approximately 60% of U.S. adults have a genetic mutation that makes it challenging for their bodies to create enough L-5-methylfolate from dietary sources.
Depression and L-5-methylfolate The role of L-5-methylfolate in the treatment of patients with depression has once again been highlighted by an article published in the American Journal of Psychiatry in 2016.
What does L-Methylfolate do for you L-Methylfolate is a medical food for use in people who have conditions related to folate deficiency. L-Methylfolate is also used in people with major depressive disorder who have folate deficiency, or in people with schizophrenia who have hyperhomocysteinemia related to folate deficiency.
Are L-5-Methyltetrahydrofolate and folic acid the same? Folate or folic acid is in fact Vitamin B9. L-5-Methyltetrahydrofolate is the more active and natural form of folate. Folic acid is the synthetic form of folate.
Doose of L-5-Methylfolate with pregnant people For pregnant women, L-5-Methylfolate is very important because pregnant women with low L-5-Methylfolate levels have an increased risk of having a baby with neural tube defects and other abnormalities. The US Public Health Service recommends that women of childbearing age take L-5-Methylfolate 400 mcg daily. Many studies suggest more intake of L-5-Methylfolate, especially at least 3 months before and during pregnancy and lactation. After the pregnancy’s first 3 months, 4 mg of methyl folate is recommended in high-risk women.
How to use L-5-methylfolate | Magnafolate Take L-5-methylfolate by mouth with or without food as directed by your doctor, usually once daily. If you are taking the over-the-counter product, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.
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