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How to choose correct methylfolate ?
In fact, the folate which the human body really needs is L-5-methyltetrahydrofolate calcium which is the pure “L” or “6(S)” isomer of methylfolate and biologically active, with the CAS NO. 151533-22-1. The “D” or “R” forms of methylfolate are not as good because they are less bioavailable. Even that is harmful for our body and . So, when you select the supplements with methylfolate, pls make sure the pure L/6S form they have.
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How to get enough folate ?
Folates from food sources, such as dark leafy greens and legumes, are absorbed through your intestinal wall. After being absorbed, dietary food folates must go through several enzymatic steps before becoming usable by your body. There are a number of dietary folate food forms; however, it may be challenging to get enough folate from your daily food intake, mainly because most individuals do not eat adequate amounts of leafy vegetables every day.
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Can methylfolate help with depression?
A clinical study of L-Methylfolate for antidepressants conducted by ALFASIGMA in US has demonstrated the benefit of a daily supplement of 15mg of LMF for patients with and without SSRI partial response and major depression. 50% among patients who were given LMF at 15mg/day had a reduction in depressive symptoms within 30 days. 84% had a significantly relieved.
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Do you know the difference between Magnafolate and folic acid ?
70% of the global population cannot metabolize Folic Acid into Folate due to a genetic mutation, while Magnafolate can be absorbed directly. when taking folic acid, unmetabolized folic acid (UMFA ) would be produced because the liver has limited metabolic ability for folic acid. While Magnafolate is much safer and doesn’t bring UMFA.
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It's urgent for us to use active folate ( Magnafolate) to alternative Folic Acid.
With the unique C crystal form, it enjoys good stability and purity. It can be stable for 3 years under room temperature. It's very important, because good stability will bring you a easier storage conditon and longer shelf life for the finished formulation.
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Do you know the potential dangers caused by folic acid ?
Folate is absorbed in the gut while Folic Acid is absorbed in the Liver. The Liver is easily saturated and can lead to unmetabolized Folic Acid in the bloodstream. Unabsorbed Folic Acid in the blood, can cause health problems for people treated for leukemia, arthritis, abnormal pregnancy, men with a family history of bowel cancer, clogged arteries, and vitamin B deficiency.
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