For almost 20 years, we have become the most professional manufacturer in the world, No.1 in China in the methylfolate industry. With strict quality guarantee system, strong brand awareness and high-level after sale service, our company is famous for the business philosophy “Only manufacture and supply premium quality products.”
In order for folic acid to remove homocysteine, it first must be converted to its active form called L-methylfolate (5-MTHF).
Jinkang Pharma is the only legal manufacturer protected by law with the production license of L-methylfolate in China.
Magnafolate® (Folate, Methylfolate, Levomefolic acid, L-5-methyltetrahydrofolate, L-5-MTHF) is a patented C-Crystal form of L-5-Methyltetrahydrofolate Calcium Salt. Key advantages over current Folate include the following: better stability (2+years at room temperature), better particle size distribution, better dissolution, higher potency, and better bioavailability. Replacement for Folic acid, Generic Type L-5-Methyltetrahydrofolate.
There is widespread agreement that maintaining adequate folate status is critical to prevent diseases due to folate inadequacy (e.g., anemia, birth defects, and cancer). However, there are concerns of potential adverse effects of excess folic acid intake and/or elevated folate status, with the original concern focused on exacerbation of clinical effects of vitamin B-12 deficiency and its role in neurocognitive health. More recently, animal and observational studies have suggested potential adverse effects on cancer risk, birth outcomes, and other diseases.
Daily 266mcg folic acid intake is disrupting our normal folate metabolism Actually, DHFR enzyme plays an important role during folate metabolism. The function of DHFR is to decompose natural folate and synthetic folic acid into active folate (5-MTHF) . DHFR acts quickly on natural folate, but slowly on folic acid. It can only metabolize about 266 mcg folic acid per day. Taking folic acid more than 266mcg, the Unmetabolized folic acid(UMFA) will build up in our body.
What our body really need is L-5-MTHF( L-5-Methyltetrahydrofolate ). But we can’t absorb it directly. Later, scientist made it into salt form. When we eat salt L-5-MTHF, it will be dissolved into Ionic form and be absorbed by ionic channel in our body. The most popular salt form is Calcium salt.
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