Does good dissolution mean good bioavailability?

Does good dissolution mean good bioavailability?


The answer is no. Dissolution and bioavailability are two different concepts.

 good bioavailability

In theory, the bioavailability is 100% when the drug is injected intravenously. However, when the drug is taken in other ways, for example ,oral , the bioavailability will decrease due to incomplete absorption and first-pass effects. Bioavailability is always used to evaluate the absorptive degree of the drugs or ingredient.

It’s an important property for L-Methylfolate and important tool in pharmacokinetics.

 

Jinkang has done a pre-clinical study in rats in order to assess the bioavailability of MAGNAFOLATE® in comparison to Glucosamine Salt L-5-Methyltetrahydrofolate.It shows Magnafolate has 8.26% higher thanGlucosamine Salt.

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