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How should we get right folate?
How should we get right folate? The best dietary sources of natural folate include fresh fruits, leafy greens, yeast, and legumes, but these can easily be degraded during food prep and cooking; this means that those foods often become less nutritious sources of folate as soon as they’re manipulated, i.e. chopped or cooked.
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Which isomers are present in the nutrient? Is L or (6S) best? What about (6S)+(6R) or DL?
Methylfolate can be quickly manufactured as a material that has both the 6S and 6R isomers (or L and D respectively).
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Why is folate important?
Why is folate important? Folate is an essential nutrient best known for supporting neural tube development during pregnancy. But for everyone else, folate is still a must-have. It’s involved in multiple processes, including DNA methtylation.
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The importance of L-5-Methyltetrahydrofolate
Many individuals don't get sufficient 5-MTHF (L-5-Methyltetrahydrofolate), the active form of folic acid, because they have intestinal or liver dysfunction, or because they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into active 5-MTHF.* A deficiency of folic acid has been linked to low-birth-weight infants and neural tube defects, which is why the Centers for Disease Control recommends folic acid supplementation for all women of childbearing age. Since 5-MTHF also contributes to the production of serotonin, melatonin, dopamine, epinephrine, and norepinephrine, supplementation supports healthy mood.
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What Studies Have Shown about 5-MTHF?
What Studies Have Shown about 5-MTHF? Many studies have been conducted over the years comparing supplementation of 5-MTHF with that of folic acid and the two main advantages (of 5-MTHF) that have been found are...
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What Does L-5-methylfolate Do
What Does L-5-methylfolate Do? L-5-methylfolate (together with vitamin B12) functions as a methyl group donor in a range of metabolic and nervous system processes, making it vital to numerous metabolic pathways in the body. L-5-methylfolate plays an essential role in methylation, it enables the conversion of homocysteine to methionine, the production of serotonin and melatonin, and it is indirectly involved in the synthesis of DNA.
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